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Cognitive Dysfunction and Quality of Life after Subarachnoid Hemorrhage (SAH)




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Principal Investigator:


Dr. Stephan Mayer
Department of Neurology
Division of Critical Care Neurology

Co-Investigators:


Dr. Robert Solomon
Department of Neurosurgery
Dr. Yaakov Stern
Department of Neurology

This is a prospective, cross-sectional observational study designed to (1) identify specific pathophysiologic processes during the acute phase of SAH associated with early (3 month) and late (12 month) cognitive or emotional dysfunction, and (2) to evaluate the clinical relevance of cognitive or emotional dysfunction after SAH in terms of their impact on life satisfaction and objective quality of life (QOL).

Potential subjects include male and non-pregnant females 18 years of age and older, who have sustained a SAH confirmed by CT or lumbar puncture. In addition to standard clinical evaluation and treatment for SAH, at discharge a brief neurologic examination and mental status test (orientation to time, place, etc.) will be performed. The subject will then return for a three hour follow-up evaluation at 3 and 12 months after SAH, in order to evaluate their long-term neurological status, disability, emotional status, cognitive functioning, and overall quality of life. Subjects unable to return in-person, will be assessed in a less detailed one hour telephone interview with the subject and/or their caregiver




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Affiliated with New York-Presbyterian Hospital || Last updated: August 2, 2010 | Comments